![]() Seek medical care if you are over 60, have a weakened immune system, are pregnant, or are of Filipino or African heritage, and you develop the signs and symptoms of valley fever, especially if you: Meningitis - an infection of the membranes and fluid surrounding the brain and spinal cord.Painful, swollen joints, especially in the knees or ankles.Painful lesions in the skull, spine or other bones.Nodules, ulcers and skin lesions that are more serious than the rash that sometimes occurs with initial infection.Signs and symptoms of disseminated disease depend on the body parts affected and may include: Most often these parts include the skin, bones, liver, brain, heart, and the membranes that protect the brain and spinal cord (meninges). It occurs when the infection spreads (disseminates) beyond the lungs to other parts of the body. The most serious form of the disease, disseminated coccidioidomycosis, is uncommon. Blood-tinged sputum (matter discharged during coughing).This complication is most common in people with weakened immune systems. ![]() If the initial coccidioidomycosis infection doesn't completely resolve, it may progress to a chronic form of pneumonia. The disease's severity depends on several factors, including your overall health and the number of fungus spores you inhale. Fatigue and joint aches can last even longer. If you develop symptoms, especially severe ones, the course of the disease is highly variable. The nodules typically don't cause problems, but they can look like cancer on X-rays. You may find out when you have a positive skin or blood test or when small areas of residual infection in the lungs (nodules) show up on a routine chest X-ray. If you don't become ill or have symptoms from valley fever, you may only find out you've been infected later. Red, spotty rash, mainly on lower legs but sometimes on the chest, arms and back.Symptoms can range from minor to severe, including: Signs and symptoms occur one to three weeks after exposure. The initial, or acute, form of coccidioidomycosis is often mild, with few or no symptoms. This initial, acute illness can develop into a more serious disease, including chronic and disseminated coccidioidomycosis. Valley fever is the initial form of coccidioidomycosis infection.
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